Vizon SciTec Inc. – Toxicology Group
The acute toxicity of monoethanolamine (MEA), diethanolamine (DEA), diethylene glycol (DEG), and triethylene glycol (TEG) were selectively tested using the following test methods and species:
Amines |
Glycols |
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MEA |
DEA |
DEG |
TEG |
|
Acute 96-hr Rainbow Trout Survival Test (EPS 1/RM/9) |
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Acute 48-hr Daphnia magna Survival Test (EPS 1/RM/11) |
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Acute 96-hr Hyalella azteca Survival Test (EPS 1/RM/33) |
The LC50s and 95% confidence limits, based on nominal concentrations, were as follows:
Amines (mg/L) |
Glycols (g/L) |
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MEA |
DEA |
DEG |
TEG |
|
96-hr Rainbow Trout |
105 (85, 145) |
460 (250, 625) |
66 (50, 100) |
N/A |
48-hr Daphnia magna |
66.7 (60.1-74.1) |
N/A |
62.63 (57.63-68.07) |
N/A |
96-hr Hyalella azteca |
170 (163-177) |
344 (312-377) |
65.98 (61.69-70.56) |
43.5 (39.4, 48.1) |
The measured concentrations at test initiation and completion were generally within 20% of nominal concentrations, indicating that the test substance concentrations were satisfactorily maintained during the exposure periods. The ranges of values (%measured/nominal) are presented below:
MEA |
DEA |
DEG |
TEG |
|
96-hr Rainbow Trout |
93-101% |
96-110% |
83-106% |
N/A |
48-hr Daphnia magna |
85-118% |
N/A |
92-105% |
N/A |
96-hr Hyalella azteca |
79-104% |
93-100% |
84-91% |
83-90% |